|
|
|
|
|
By AR Welch, Editorial & Community Director, Advancing RNA | Welcome to Advancing RNA’s mRNA Hot Takes, the show where we talk about serious RNA things, but with a spicy twist. Here, in episode 5, Advancing RNA's ARW sits down with Radar Therapeutics' Sophia Lugo and Entrée Bio's Michelle Lynn Hall to answer the (loaded) question: To do good science in the mRNA sector, should we be staying in the US? | |
|
|
|
By Steven Wolk, Ph.D., Sinawali Biotechnology Solutions | Precise CRISPR delivery remains the bottleneck to safer, more potent gene editing. Advances in LNP design, targeting strategies, and extrahepatic delivery are redefining what’s possible in vivo. | |
|
|
|
By Bill Jarvis, James Golden, and Jim Love, CRB Group | As oligos move toward larger indications, manufacturing shifts from chemistry alone to facility design—balancing scale, solvent safety, cost, and flexibility as SPOS, slurry, and enzymatic paths converge. | |
|
|
|
In this Advancing RNA Live clip, CMC consultant Sujit Jain unpacks the levels of maturity he’s observed in process and analytical development, as well as supply chain. While vaccines and liver-targeting therapeutics boast what we can call a reproducible platform today, targeted LNP therapies introduce a handful of scale-up sensitivities and characterization hurdles. |
|
|
|
| Benefits Of Isolator Technology In Fill-Finish | Article | By Sabrina Zirkle, Jubilant HollisterStier | Isolator technology enhances sterility assurance, reduces contamination risk, improves operator safety, and supports regulatory compliance, making it essential for modern aseptic fill-finish operations. |
|
|
| Reducing Human Variability In Bioanalysis | Article | Dash Bio | Automation removes manual variability, creating consistent, repeatable processes that improve precision, strengthen compliance, and produce more reliable data for critical decisions. |
|
|
| mRNA Purification At Ambient Temperature | Application Note | MilliporeSigma | Explore how anion exchange chromatography with dual gradient elution enables efficient mRNA purification at ambient temperature. |
|
|
|
|
|
|
|
|
|
|
|
.png){kind=logo}
