Deciphering mRNA Immunogenicity: The What, Why, And How Of Early Assessment Of Human Immune Response Of Your Molecule Candidate

This webinar dives into the complexities of immunogenicity, the body's response to a treatment. Many factors influence this response, including the treatment itself, the patient's condition, and how the treatment is given. While some factors are unpredictable, scientists can use lab tools to assess the treatment itself.

Focus on mRNA Therapeutics

• Unlike some medications, mRNA therapeutics may be designed to trigger an immune response (like vaccines). It's crucial to ensure a safe and appropriate immune reaction.
• To design the right immunogenicity study, we consider the specific mRNA, the delivery system (LNP), and the intended use of the treatment.

What You'll Learn:

• The various factors affecting your molecule's potential to trigger an immune response and why understanding these factors early is important.
• Strategies for assessing immunogenicity in mRNA therapeutics, including in silico and in vitro tools.