RNA Supply Chain Solutions

  1. High-Fidelity Nuclease For Therapeutic Breakthroughs 10/28/2024

    The hfCas12Max nuclease offers superior gene editing with high fidelity, broad PAM recognition, minimal off-target effects, and compatibility across cell types for therapeutic applications.

  2. Advancing Innovative Plasmid DNA Manufacturing Solutions For CGT 3/13/2025

    Having produced over 185,000 DNA lots, including 5,000+ cGMP batches, we are a trusted partner in plasmid DNA production from discovery to commercialization.

  3. Nanoplasmid™ Vector Platform 5/5/2026

    With gene therapy advancing at a record pace, Aldevron recognizes the enormous promise your work can bring to therapeutics. We are proud to deliver a superior, modern plasmid technology to your therapeutic endeavors.

  4. Synthetic Research Grade sgRNA Manufacturing For CRISPR Experiments 11/28/2023

    Consistently achieve high editing efficiency and quick turnaround time in as little as 7 days with synthetic sgRNA that pave your way to a successful CRISPR experiment.

  5. Plasmid DNA Production 6/23/2022

    Integrated manufacturing supporting cell and gene therapies.

    The critical genetic foundation for advanced therapies

    Plasmid DNA is a critical raw material for advanced therapies and mRNA synthesis, supporting their transfection to enable rapid advancement of the therapeutic product. Center for Breakthrough Medicines (CBM) offers capacity dedicated to the development and manufacture of high quality plasmid DNA and other nucleic acids.

  6. Prima Product Line Up 3/17/2026

    Discover how specialized RNA polymerase variants solve yield, purity, and capping challenges across different template lengths, with substantive improvements over standard T7 polymerase performance.

  7. in vivo-jetRNA®+ 9/14/2022

    Efficient: 100% mRNA encapsulation leading to comparable LNP delivery results
    in vivo-jetRNA®+ is the reagent of choice to deliver mRNA to various organs. This is attributable to its intrinsic properties: in vivo-jetRNA®+ protects its payload against ubiquitous endonucleases, prevent non-specific interactions with proteins and promote efficient cell entry.

  8. mRNA Raw Materials: Supporting Your Journey To Market 12/5/2025

    Implementing a quality-by-design approach for manufacturing inputs limits contamination risks and simplifies regulatory compliance. Validated processes ensure consistency when scaling operations.

  9. in vivo mRNA Delivery Using Liposome-Based Reagent 12/12/2022

    in vivo-jetRNA®+ is a ready-to-use reagent that does not require formulation equipment that leads to 100% mRNA encapsulation leading to efficient mRNA delivery.

  10. INDe sgRNAs For Preclinical Safety, Toxicity, And Efficacy Studies 11/29/2023

    Seamlessly transition from discovery to delivery with INDe sgRNAs. These quality sgRNAs can be synthesized in quantities from milligrams to grams and follow high purity specifications.