RNA Supply Chain Solutions

  1. GenVoy-ILM™ T Cell Kit For mRNA, Ignite™ 7/1/2022

    GenVoy-ILM™ T Cell Kit for mRNA, Ignite is an lipid nanoparticle (LNP) reagent mix optimized for the delivery of messenger RNA (mRNA) or Cas9 mRNA/sgRNA into activated human primary T cells.

  2. GMP sgRNA Manufacturing 11/30/2023

    Transition from early-phase research through process development into the clinic with these continuum sgRNA available in different grades.

  3. Plasmid DNA Production 6/23/2022

    Integrated manufacturing supporting cell and gene therapies.

    The critical genetic foundation for advanced therapies

    Plasmid DNA is a critical raw material for advanced therapies and mRNA synthesis, supporting their transfection to enable rapid advancement of the therapeutic product. Center for Breakthrough Medicines (CBM) offers capacity dedicated to the development and manufacture of high quality plasmid DNA and other nucleic acids.

  4. Excellence For Cell And Gene Therapy Manufacturing 6/4/2025

    Unlock the potential of advanced therapies with dedicated partnership and tailored manufacturing solutions, ensuring quality and efficiency from discovery through to delivery for next-generation treatments.

  5. Process Chemicals For RNA Drug Manufacturing

    Make use of our portfolio of raw materials required for mRNA with an integrated offering for all process steps, from plasmid DNA (pDNA) to mRNA synthesis to final formulation.

  6. in vivo mRNA Delivery Using Liposome-Based Reagent 12/12/2022

    in vivo-jetRNA®+ is a ready-to-use reagent that does not require formulation equipment that leads to 100% mRNA encapsulation leading to efficient mRNA delivery.

  7. jetMESSENGER®: mRNA Transfection Reagent 3/21/2023

    Take your gene expression to the next level by switching to mRNA!

    Primary cells, neurons, suspension cells and various cancer cell lines are especially challenging to transfect. jetMESSENGER® gives high transfection efficiency in all of these usually difficult to transfect cells, by allowing highly efficient mRNA transfection.

    mRNA transfection is as easy as DNA transfection, with the advantage that mRNA does not need to reach the cell nucleus for expression nor require cell division for efficient gene expression. Hence, cells that are slow dividing or that have developed specific mechanisms to protect their genome can finally be used for gene expression.

    Unravel the full potential of your cells by switching to mRNA transfection.

  8. Advancing Innovative Plasmid DNA Manufacturing Solutions For CGT 3/13/2025

    Having produced over 185,000 DNA lots, including 5,000+ cGMP batches, we are a trusted partner in plasmid DNA production from discovery to commercialization.

  9. T Cell Kit For mRNA On NanoAssemblr Spark 4/14/2022

    The GenVoy-ILM T Cell Kit for mRNA is optimized for the delivery of mRNA into activated primary human T cells using mRNA-LNPs formulated on the NanoAssemblr Spark instrument and cartridges.

  10. Mitigate Contamination Risks With HTST Flash Pasteurization 5/2/2024

    Gibco™ High-temperature, short-time (HTST) treatment of raw materials

    HTST treatment currently available in North America

    Simple sugar batch sizes ranging from 800 to 8,800 L

    In-house HTST preparation can be expensive and cumbersome. Outsourcing this technology to Thermo Fisher Scientific can alleviate production bottlenecks and increase viral mitigation confidence.

    Suitable and cost-effective for large volumes

    Standard and custom bioprocessing containers available (5 L–1,000 L). Please contact your sales representative.