RNA Supply Chain Solutions

  1. Fit-For-Purpose And GMP Grade mRNA Reagents 3/24/2025

    Ensure the safety and efficacy of your mRNA therapeutics with high-quality, GMP-grade reagents from a trusted partner with a multi-tiered quality approach to deliver manufacturing certainty.

  2. Plasmid DNA Manufacturing 1/31/2023

    As a critical starting material in the production of many advanced therapies including viral vectors and RNA vaccines, cell and gene therapy research at any scale requires plasmid DNA manufacturing. Our specialists provide custom plasmid production that fits your project specifications. To save time and accelerate your cell and gene therapy programs, we also offer off-the-shelf, premanufactured, High Quality viral vector packaging plasmids.

  3. Process Chemicals For RNA Drug Manufacturing

    Make use of our portfolio of raw materials required for mRNA with an integrated offering for all process steps, from plasmid DNA (pDNA) to mRNA synthesis to final formulation.

  4. Prima Product Line Up 3/17/2026

    Discover how specialized RNA polymerase variants solve yield, purity, and capping challenges across different template lengths, with substantive improvements over standard T7 polymerase performance.

  5. Advancing Innovative Plasmid DNA Manufacturing Solutions For CGT 3/13/2025

    Having produced over 185,000 DNA lots, including 5,000+ cGMP batches, we are a trusted partner in plasmid DNA production from discovery to commercialization.

  6. mRNA Raw Materials: Supporting Your Journey To Market 12/5/2025

    Implementing a quality-by-design approach for manufacturing inputs limits contamination risks and simplifies regulatory compliance. Validated processes ensure consistency when scaling operations.

  7. jetMESSENGER®: mRNA Transfection Reagent 3/21/2023

    Take your gene expression to the next level by switching to mRNA!

    Primary cells, neurons, suspension cells and various cancer cell lines are especially challenging to transfect. jetMESSENGER® gives high transfection efficiency in all of these usually difficult to transfect cells, by allowing highly efficient mRNA transfection.

    mRNA transfection is as easy as DNA transfection, with the advantage that mRNA does not need to reach the cell nucleus for expression nor require cell division for efficient gene expression. Hence, cells that are slow dividing or that have developed specific mechanisms to protect their genome can finally be used for gene expression.

    Unravel the full potential of your cells by switching to mRNA transfection.

  8. High-Fidelity Nuclease For Therapeutic Breakthroughs 10/28/2024

    The hfCas12Max nuclease offers superior gene editing with high fidelity, broad PAM recognition, minimal off-target effects, and compatibility across cell types for therapeutic applications.

  9. Mitigate Contamination Risks With HTST Flash Pasteurization 5/2/2024

    Gibco™ High-temperature, short-time (HTST) treatment of raw materials

    HTST treatment currently available in North America

    Simple sugar batch sizes ranging from 800 to 8,800 L

    In-house HTST preparation can be expensive and cumbersome. Outsourcing this technology to Thermo Fisher Scientific can alleviate production bottlenecks and increase viral mitigation confidence.

    Suitable and cost-effective for large volumes

    Standard and custom bioprocessing containers available (5 L–1,000 L). Please contact your sales representative.

  10. in vivo-jetRNA®+ 9/14/2022

    Efficient: 100% mRNA encapsulation leading to comparable LNP delivery results
    in vivo-jetRNA®+ is the reagent of choice to deliver mRNA to various organs. This is attributable to its intrinsic properties: in vivo-jetRNA®+ protects its payload against ubiquitous endonucleases, prevent non-specific interactions with proteins and promote efficient cell entry.