RNA Supply Chain Solutions

1. jetMESSENGER®: mRNA Transfection Reagent For Hard-To-Transfect Cells 3/21/2023

   Learn about a highly efficient and gentle mRNA transfection reagent designed for outstanding transfection efficiency in hard-to-transfect cells, finally allowing relevant gene expression experiments in almost all cell types.

2. Excellence For Cell And Gene Therapy Manufacturing 6/4/2025

   Unlock the potential of advanced therapies with dedicated partnership and tailored manufacturing solutions, ensuring quality and efficiency from discovery through to delivery for next-generation treatments.

3. Plasmid DNA Production 6/23/2022

   Integrated manufacturing supporting cell and gene therapies.

   The critical genetic foundation for advanced therapies

   Plasmid DNA is a critical raw material for advanced therapies and mRNA synthesis, supporting their transfection to enable rapid advancement of the therapeutic product. Center for Breakthrough Medicines (CBM) offers capacity dedicated to the development and manufacture of high quality plasmid DNA and other nucleic acids.

4. T Cell Kit For mRNA On NanoAssemblr Spark 4/14/2022

   The GenVoy-ILM T Cell Kit for mRNA is optimized for the delivery of mRNA into activated primary human T cells using mRNA-LNPs formulated on the NanoAssemblr Spark instrument and cartridges.

5. Brochure: The Power Of Small: Nanoplasmid™ Vector Platform 1/19/2023

   With gene therapy advancing at a record pace, Aldevron recognizes the enormous promise your work can bring to therapeutics. We are proud to deliver a superior, modern plasmid technology to your therapeutic endeavors.

6. INDe sgRNAs For Preclinical Safety, Toxicity, And Efficacy Studies 11/29/2023

   Seamlessly transition from discovery to delivery with INDe sgRNAs. These quality sgRNAs can be synthesized in quantities from milligrams to grams and follow high purity specifications.

7. Plasmid DNA Manufacturing 1/31/2023

   As a critical starting material in the production of many advanced therapies including viral vectors and RNA vaccines, cell and gene therapy research at any scale requires plasmid DNA manufacturing. Our specialists provide custom plasmid production that fits your project specifications. To save time and accelerate your cell and gene therapy programs, we also offer off-the-shelf, premanufactured, High Quality viral vector packaging plasmids.

8. jetMESSENGER®: mRNA Transfection Reagent 3/21/2023

   Take your gene expression to the next level by switching to mRNA!

   Primary cells, neurons, suspension cells and various cancer cell lines are especially challenging to transfect. jetMESSENGER® gives high transfection efficiency in all of these usually difficult to transfect cells, by allowing highly efficient mRNA transfection.

   mRNA transfection is as easy as DNA transfection, with the advantage that mRNA does not need to reach the cell nucleus for expression nor require cell division for efficient gene expression. Hence, cells that are slow dividing or that have developed specific mechanisms to protect their genome can finally be used for gene expression.

   Unravel the full potential of your cells by switching to mRNA transfection.

9. Advancing Innovative Plasmid DNA Manufacturing Solutions For CGT 3/13/2025

   Having produced over 185,000 DNA lots, including 5,000+ cGMP batches, we are a trusted partner in plasmid DNA production from discovery to commercialization.

10. GMP sgRNA Manufacturing 11/30/2023

    Transition from early-phase research through process development into the clinic with these continuum sgRNA available in different grades.