RNA Supply Chain Solutions

1. Plasmid DNA Production 6/23/2022

   Integrated manufacturing supporting cell and gene therapies.

   The critical genetic foundation for advanced therapies

   Plasmid DNA is a critical raw material for advanced therapies and mRNA synthesis, supporting their transfection to enable rapid advancement of the therapeutic product. Center for Breakthrough Medicines (CBM) offers capacity dedicated to the development and manufacture of high quality plasmid DNA and other nucleic acids.

2. Fit-For-Purpose And GMP Grade mRNA Reagents 3/24/2025

   Ensure the safety and efficacy of your mRNA therapeutics with high-quality, GMP-grade reagents from a trusted partner with a multi-tiered quality approach to deliver manufacturing certainty.

3. GMP sgRNA Manufacturing 11/30/2023

   Transition from early-phase research through process development into the clinic with these continuum sgRNA available in different grades.

4. T Cell Kit For mRNA On NanoAssemblr Spark 4/14/2022

   The GenVoy-ILM T Cell Kit for mRNA is optimized for the delivery of mRNA into activated primary human T cells using mRNA-LNPs formulated on the NanoAssemblr Spark instrument and cartridges.

5. GenVoy-ILM™ T Cell Kit For mRNA, Ignite™ 7/1/2022

   GenVoy-ILM™ T Cell Kit for mRNA, Ignite is an lipid nanoparticle (LNP) reagent mix optimized for the delivery of messenger RNA (mRNA) or Cas9 mRNA/sgRNA into activated human primary T cells.

6. Synthetic Research Grade sgRNA Manufacturing For CRISPR Experiments 11/28/2023

   Consistently achieve high editing efficiency and quick turnaround time in as little as 7 days with synthetic sgRNA that pave your way to a successful CRISPR experiment.

7. Process Chemicals For RNA Drug Manufacturing

   Make use of our portfolio of raw materials required for mRNA with an integrated offering for all process steps, from plasmid DNA (pDNA) to mRNA synthesis to final formulation.

8. in vivo mRNA Delivery Using Liposome-Based Reagent 12/12/2022

   in vivo-jetRNA^®+ is a ready-to-use reagent that does not require formulation equipment that leads to 100% mRNA encapsulation leading to efficient mRNA delivery.

9. Advancing Innovative Plasmid DNA Manufacturing Solutions For CGT 3/13/2025

   Having produced over 185,000 DNA lots, including 5,000+ cGMP batches, we are a trusted partner in plasmid DNA production from discovery to commercialization.

10. INDe sgRNAs For Preclinical Safety, Toxicity, And Efficacy Studies 11/29/2023

    Seamlessly transition from discovery to delivery with INDe sgRNAs. These quality sgRNAs can be synthesized in quantities from milligrams to grams and follow high purity specifications.