RNA Outsourcing Videos

1. No Cells, No Limits To DNA Production: Inside Synthetic DNA 6/12/2025

   Here, we walk you through our groundbreaking, enzymatic DNA manufacturing process that enables the production of linear DNA templates for IVT mRNA synthesis — without the use of cells.

2. An Early Formulation Screening Service 5/23/2024

   Gain insights into overcoming the challenges in lipid nanoparticle (LNP) formulation, explore critical aspects of the process and analytical development of LNPs, and much more.

3. How Are The Costs Of mRNA-LNP Manufacturing Evolving? 2/10/2025

   Achieving cost-effective manufacturing while maintaining high quality standards today is one of the biggest challenges facing companies outsourcing mRNA/RNA development. In turn, panelists Qian Ruan, Andy Geall, and Alex Aust reflect on how and where they’ve seen the costs of mRNA-LNP manufacturing evolving/fluctuating in recent years.

4. How Outsourcing mRNA Development Has Evolved Since COVID 2/10/2025

   Advancing RNA panelists Alex Aust, Qian Ruan, and Andy Geal share their thoughts on the ways in which outsourcing firms are approaching mRNA development today, as well as why outsourcing — as opposed to building a GMP facility — remains critical for (x)RNA biotechs today.

5. Scale-Up And Production Of Key Lipids Used In mRNA Delivery Systems 2/13/2025

   Discover key strategies for overcoming challenges in the industrial-scale production of ionizable and PEG lipids to optimize mRNA vaccine formulation and address critical manufacturing requirements.

6. mRNA Capabilities 3/4/2025

   Discover how our advanced capabilities in Hopkinton, MA, are overcoming the challenges of large-scale RNA therapeutic manufacturing, enabling the efficient production of complex srRNA and mRNA therapies.

7. The Synergistic Role Of Drug Safety In Clinical Trial Operations 4/25/2024

   Delve into the significance of adept interpersonal leadership within your drug safety program, shedding light on the operational and financial benefits that stem from fostering a collaborative environment.

8. Don't Forget These Important Points When Selecting An RNA CDMO 8/22/2024

   Together, Omega’s Jeff Atkinson & Sail Biomedicines’ Jim Nolan share their perspectives on the health of the linear mRNA and circRNA outsourcing sector.

9. LNP And Liposomal Center Of Excellence 3/10/2026

   A connected development pathway supports smoother scale-up and greater consistency for LNP-based therapeutics. Explore how integrated expertise across key stages helps teams accelerate progress.

10. Forecasting the Transition from SPOS to Enzymatic Ligation for gRNA 4/29/2026

    In this clip, Advancing RNA Live panelist Venkat Krishnamurthy unpacks how solid-phase synthesis has been improving to overcome current challenges with gRNA production, while Max De Long and April Sena share their perspectives on the maturity of current CDMO platforms for enzymatic ligation of gRNA.