RNA Outsourcing Videos

1. How A Sponsored CMC Platform Accelerates mRNA Projects Into The Clinic 1/31/2023

   Developing a client-sponsored Target Product Profile (TPP) and Analytical Target Profile (ATP) is critical to move your drug product to clinic efficiently and meet acceptance criteria.

2. Don't Forget These Important Points When Selecting An RNA CDMO 8/22/2024

   Together, Omega’s Jeff Atkinson & Sail Biomedicines’ Jim Nolan share their perspectives on the health of the linear mRNA and circRNA outsourcing sector.

3. Scale-Up And Production Of Key Lipids Used In mRNA Delivery Systems 2/13/2025

   Discover key strategies for overcoming challenges in the industrial-scale production of ionizable and PEG lipids to optimize mRNA vaccine formulation and address critical manufacturing requirements.

4. How Can Sponsors & CDMOs Collaborate On RNA Analytical/Process Development? 8/22/2024

   Having worked on both the innovator and CDMO sides of the industry, Advancing RNA LIVE panelist Khaled Yamout outlines where he sees the greatest weaknesses in these critical sponsor-CDMO partnerships and offers guidance.

5. How To Bring Your LNP Formulation To Clinical/Commercial Manufacturing 5/23/2024

   Gain valuable insights into key considerations when selecting lipid excipients for LNP formulations and the process development steps necessary to advance them to GMP manufacturing and clinical trials.

6. Who's In Charge? How To Ensure Effective Trial Oversight, Leadership 3/19/2025

   Gain valuable insights into the role of sponsor-side Clinical Operations leadership, the risks of over-relying on CROs, and key strategies for fostering collaboration between sponsors and partners.

7. The Latest And Greatest Technological Innovations In mRNA-LNP Production 2/10/2025

   In this segment, Replicate Biosciences’ Andy Geall, Qian Ruan, & Alex Aust identify the most promising technological and raw material innovations that are influencing the drug substance and drug product production processes at CDMOs.

8. Customized mRNA Processing For Improved Therapy Development And Manufacturing 2/13/2025

   Optimize mRNA development by learning key strategies for process refinement, critical component identification, and in-process analytics to enhance therapeutic production.

9. A Deeper Dive On Mitigating Financial Risk Before Selecting A Vendor 1/23/2024

   In part two of this webinar series, presenters focus on avoiding potential risks, such as unexpected budget changes and unplanned change orders, that could jeopardize the success of a clinical trial.

10. Intelligent mRNA Manufacturing Through Process Analytical Technologies 3/10/2025

    Learn how predictive models can monitor key CQAs, such as RNA concentration and nucleoside triphosphate consumption, and explore RBP and MIT’s vision for revolutionizing biomanufacturing.