RNA Manufacturing Videos

  1. How Are The Costs Of mRNA-LNP Manufacturing Evolving? 2/10/2025

    Achieving cost-effective manufacturing while maintaining high quality standards today is one of the biggest challenges facing companies outsourcing mRNA/RNA development. In turn, panelists Qian Ruan, Andy Geall, and Alex Aust reflect on how and where they’ve seen the costs of mRNA-LNP manufacturing evolving/fluctuating in recent years.

  2. Crafting A "Durable" Partnership: A Two-Pronged Approach

    Featured speakers for the "Got Raw Materials? The State Of The mRNA Supply Chain" event share how they are working to deepen their partnerships today.

  3. LNP And Liposomal Center Of Excellence 3/10/2026

    A connected development pathway supports smoother scale-up and greater consistency for LNP-based therapeutics. Explore how integrated expertise across key stages helps teams accelerate progress.

  4. Beyond Purity: Addressing the FDA's CMC Expectations for gRNA 4/29/2026

    Advancing RNA Live panelists Venkat Krishnamurthy, April Sena, and Max De Long share their perspectives on the most important regulatory considerations for gRNA production utilizing an enzymatic ligation approach.

  5. Scale Up: Bringing Nanomedicine From The Lab To The Clinic 4/13/2022

    We discuss key components and common pain points of scaling up nanomedicine production and use recent publications to walk customers through the process.

  6. Are We Missing mRNA Drug Substance CQAs? 6/9/2026

    As a field, we’ve been aligned around CQAs for our mRNA drug substances. However, differences in translation between highly similar mRNAs (i.e., (same sequence, same design, different manufacturers) raises the question of whether we’re missing any QAs/CQAs. Here, Advancing RNA Live panelists Elaine Peters and Ilya Shestolapov share their take. 

  7. The Biggest Challenges In Adopting Enzymatic Ligation of gRNA 4/29/2026

    In this Advancing RNA Live clip, panelists Venkat Krishnamurthy and April Sena home in on the economic, molecular, and biological challenges complicating the transition to enzymatic ligation today. 

  8. Plasmid DNA Downstream Purification Process 4/11/2023

    Large scale production of plasmid DNA requires an in-depth understanding and optimization of the entire downstream process. Explore a complete solution, from harvest to bulk filtration.

  9. Streamlining pDNA: Capacity, Complexity, And Cutting-Edge Solutions 11/20/2025

    Learn how flexible facility design and process innovation are accelerating pDNA manufacturing, as well as key strategies to avoid scale-up pitfalls and meet growing therapeutic demand.

  10. Risk Reduction In mRNA Therapeutic Development: Meet The Panel 10/16/2023

    Listen in on a discussion reviewing key drivers behind the flurry of activity in mRNA therapeutic development and begin to address the rate-limiting risks to mRNA therapeutic development.