RNA Manufacturing Videos

  1. How To Foster Greater R&D And CMC Integration In Your Organization 4/24/2023

    In this Bioprocess Online Live panel discussion explore how two industry experts encourage their CMC and R&D teams to work more closely together to ensure a streamlined transition of a molecule from R&D to process development.

  2. Smart Bioprocess Data Utilization For Advanced Analytics And Monitoring With Data Analytics Tools Purpose-Built For Bioprocessing

    We share our experience working with organizations as they adopt solutions for automated data acquisition, aggregation, visualizations, and statistical analysis.

  3. mRNA/saRNA Manufacturing: Accelerate The Path To Clinic 3/22/2021

    Discover key upstream and downstream considerations for process development for RNA drug substance manufacturing and the parameters that need construct-specific optimization to increase yield and reduce impurities.

  4. The "Short-Mer" Advantage: The Quality Gains Of siRNA Enzymatic Ligation 3/27/2026

    Is enzymatic ligation merely a "volume play"? In this segment, Advancing RNA Live speakers Claire McCleod and Jill Caswell challenge this belief, explaining the extent at which this paradigm shift also unlocks higher siRNA purity. 

  5. OligoProcess™ Oligonucleotide Synthesizer Product Overview 2/3/2025

    Meet our OligoProcess™ oligonucleotide synthesizer – exceptional scale ranges in 3 different scale designs to fit your needs up to 1800 mmol and beyond.

  6. Development Of A Mitra Tip Extraction Assay Coupled With LC-MSMS 1/15/2025

    Watch this rundown of a novel method for quantifying L-Citrulline, L-Arginine, and L-Argininosuccinic acid using Mitra tip extraction coupled with LC-MS/MS for enhanced accuracy and reproducibility.

  7. "Continuous Improvement:" Defining Your Purification Process & Product Specifications 4/24/2023

    In this Bioprocess Online Live panel discussion, we talk about where the greatest sources of variability are in our downstream processes and how companies should be approaching the question of “how pure is pure enough?"

  8. Three Leaders In mRNA Therapeutics 3/14/2022

    In this segment of the Bioprocess Online Live event mRNA Manufacturing: Bright Future, Big Challenges, we get to know leaders at three organizations bringing mRNA technology to bear in a variety of prophylactic and therapeutic capacities. Tune in and get to know Roberta Duncan, VP of the mRNA program at Seqirus; Duke Human Vaccine Institute Associate Director of Upstream and Downstream Process Development Jason Dickens, Ph.D.; and Jin Zhou, Executive Director of Process Development for mRNA and Protein Biologics at Ultragenyx. 

  9. The Purification Dilemma: Balancing Upstream & Downstream Investment 10/15/2025

    This Advancing RNA Live clip dives into the biggest challenges in mRNA purification and the critical debate on where to focus investment. Here, our three mRNA PD experts argue for a holistic process development strategy, challenging the traditional wisdom of optimizing the upstream process at any cost.

  10. How Are The Costs Of mRNA-LNP Manufacturing Evolving? 2/10/2025

    Achieving cost-effective manufacturing while maintaining high quality standards today is one of the biggest challenges facing companies outsourcing mRNA/RNA development. In turn, panelists Qian Ruan, Andy Geall, and Alex Aust reflect on how and where they’ve seen the costs of mRNA-LNP manufacturing evolving/fluctuating in recent years.