Featured Articles

  1. mRNA Manufacturing: Overcoming CMC Development Challenges 6/15/2022

    A lack of standardization and cost-effective techniques for manufacturing and analytics for product characterization create CMC challenges for mRNA-based products.

  2. New To mRNA Manufacturing? Considerations For Starting 6/15/2022

    Explore considerations for starting mRNA manufacturing related to the following topics: DNA template, mRNA product - IVT, mRNA product - purification, LNP encapsulation, and fill-finish.

  3. Oligonucleotide Development And Manufacturing Workflow 3/28/2022

    Learn more about oligo workflows and solutions for oligonucleotide process development, from scalable oligo synthesis to cleavage and deprotection, purification, and buffer exchange.

  4. Genomic Medicine And The Tools To Realize Its Potential 1/12/2022

    New technologies and collaborations driving the democratization of RNA therapeutics are creating an explosion of opportunity for companies pursuing the development of these transformative medicines.

  5. Key Insights Into Overcoming mRNA Process Challenges 9/8/2021

    Realizing the potential of mRNA requires focus on key areas and strategies that could help alleviate the bottlenecks in this growing market segment.

  6. mRNA Manufacturing Workflow 6/2/2021

    Therapies based on messenger RNA, such as mRNA vaccines, have revolutionary potential. Learn more about key objectives, considerations, and strategies in mRNA manufacturing.

  7. Downstream Bioprocess Buffer Prep: Can Machines Be Trusted? 11/8/2019

    Is automated buffer preparation a solution to the dilemma of balancing increased production capacity against limited footprint expansion alternatives?

  8. Master Analytical SEC Running Conditions 10/25/2019

    Need to find out how to calibrate your size exclusion chromatography (SEC) column? Or how different additives affect your results? Read these useful insights.

  9. New Biologic Drugs: Regulatory Challenges And Considerations 9/30/2019

    Along the drug candidate development journey there are many regulatory milestones and hurdles. Here are some tips to assist with up-front planning to alleviate headaches down the road.

  10. Scaling A mAb Production Process To A Single-Use Platform 9/27/2019

    The transfer of mAb production processes between scales is difficult. In this study, we leveraged existing physical characterization data and scaled a process from microbioreactor to production scale.