Featured Articles

1. Virus Retention Performance Under Diverse Processing Conditions 11/14/2025

   Virus filtration is robust across a wide range of process parameters, including high protein concentration and flow decay. Discover how retention relies on size exclusion to simplify risk assessment.

2. Supporting Complex Manufacturing For Liquid And Lyophilized Drug Products 10/24/2025

   Aseptic fill and finish operations gain efficiency and precision with modular isolator technology, inline weight checks, and lyophilization, which are ideal for mRNA-LNPs and other sensitive modalities.

3. Cell Culture Media Filtration: Evaluating Cell Culture Performance 10/23/2025

   Cell culture performance remained consistent across PES and PVDF filters, even under worst-case filtration conditions. Discover a practical framework for evaluating membrane impact on CHO cell growth.

4. Achieve Higher Targeted Concentrations 9/30/2025

   Single-pass TFF streamlines downstream processing by reducing footprint, shear exposure, and hold-up volumes. Learn how this approach is advancing efficiency across therapeutic and vaccine production.

5. Elevating mRNA Manufacturing Toward GMP-Readiness 8/27/2025

   The mRNA Technology Transfer Program empowers LMICs with scalable vaccine production. Learn about a partnership that drives innovation in mRNA and sets a global blueprint for equitable health access.

6. Stabilization Of RNA-Loaded Lipid Nanoparticles By Lyophilization 8/15/2025

   Discover how lyophilization enhances RNA-based therapeutics by enabling storage at higher temperatures, which simplifies cold-chain logistics while preserving nanoparticle integrity and biological activity.

7. Limiting Off-Target Effects Of CRISPR-Based Products 2/11/2025

   Find out how to enhance CRISPR gene editing specificity by using Next Generation Sequencing to improve sgRNA quality control, addressing off-target effects and ensuring higher sequence fidelity.

8. Building Local Biomanufacturing Capacity In South Africa 2/11/2025

   Biovac evolved from a vaccine supplier to a biopharmaceutical innovator, providing a blueprint for expanding Africa's vaccine manufacturing capacity. Gain valuable insights from their journey.

9. mRNA Purification Using Anion Exchange Chromatography At Ambient Temperature 12/11/2024

   Explore how anion exchange chromatography with dual gradient elution enables efficient mRNA purification at ambient temperature.

10. Software Simplifies 21 CFR Part 11 and Annex 11 Compliance 12/9/2024

    21 CFR Part 11 and Annex 11 regulate electronic records and signatures in biomanufacturing, ensuring data integrity, security, and compliance while enabling efficient processes and regulatory alignment.