In recent years, the field of messenger RNA (mRNA) has emerged as a groundbreaking technology with vast potential for revolutionizing the development of therapeutics. With tremendous versatility and a broad number of applications, mRNA-based approaches can be a pathway toward more precise, adaptable, and potentially curative treatments for a wide range of diseases.

As a novel class of therapeutics, the mRNA manufacturing process is not yet optimized or templated. Manufacturing complexity and regulatory uncertainty present further challenges. For companies advancing mRNA-based therapeutics, access to new technologies and expert services is essential for success as they ask: “How can I establish the best production process?”

MilliporeSigma, the life science business of Merck KGaA, Darmstadt, Germany, empowers you to unlock the potential of mRNA-based therapeutics. We understand the imperatives that innovators face, from enhancing molecule stability and process efficiency, to optimizing complex manufacturing workflows and navigating regulatory guidelines.

Our global organization is ready to address your specific needs with an integrated, customizable offering that encompasses:

  • Industry-leading manufacturing purification technologies
  • Bioprocessing raw materials and lipids for mRNA delivery and formulation
  • Process analytical technologies (PAT), data analytics, automation, and control software
  • Regulatory counsel and support 
  • mRNA contract development and manufacturing
  • Collaboration labs equipped with scientific experts, innovative technologies, and flexible non-GMP facilities 

Learn more about how we can help solve your mRNA manufacturing challenges. Visit our application webpages for more information on products and services for mRNA development and manufacturing and discover how we’re partnering with innovators to shape the future of this exciting field.



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