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| The oligo manufacturing landscape is evolving. Long dependent on solvent-intensive solid-phase synthesis, siRNA developers and CDMOs are beginning a critical shift toward enzymatic production—starting with enzymatic ligation. This session explores the current state of enzymatic ligation, highlighting recent advancements and the key challenges of integrating it into existing manufacturing processes. Registration is free! |
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By Anna Rose Welch, editorial and community director | It goes without saying, efficiency in drug development is tantamount—especially when it comes to getting clinical data. So, when I asked Allan Shaw about trends he anticipates seeing in 2026, he pointed to the rise of overseas development, particularly in nations like Australia and China. | |
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The Great Cell Therapy Reset: Solving The Industrial Math Of Living Drugs | By Johnathon Anderson, Ph.D. | Major players are exiting cell therapy, but this isn't a failure of biology, it is a manufacturing correction. Learn why the industry is pivoting from bespoke, unscalable ex vivo services to standardized in vivo CAR-T products to solve the industrial math of living drugs. |
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Designing mRNA For The Next Generation Of Therapeutics | By Carol Tan-Fujita, Ph.D., and Archa Fox, Ph.D. | Moving beyond vaccines, the next generation of mRNA is focused on programmable longevity and tissue specificity. Explore how engineering payloads for durability and controlled expression is essential for chronic and regenerative therapeutics. |
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| Current And Emerging Technologies To Optimize mRNA Manufacturing | Article | By Clemens Jakobi, Michał Domański, and Telmo Graça, Lonza | Explore the benefits of using mRNA for vaccines and therapeutics, and learn how to address technical, intellectual property, and cost considerations when considering commercial production. |
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| The Secret To Pure Oligos: Why AEX Rules At Scale | Article | KNAUER | Discover how anion exchange chromatography (AEX) delivers high loading capacity and clinical-grade purity while addressing common scale-up challenges like aggregation and equipment longevity. |
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| Sign up today for free exhibit hall access for INTERPHEX , April 21-23, 2026, New York City. The leading global pharmaceutical and biotechnology event that brings together essential industry innovation with expert-led education. No matter where you sit in the pharmaceutical development lifecycle, INTERPHEX provides integral solutions and networking opportunities to drive growth and fuel scalability for your business. |
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