Newsletter | August 1, 2026

08.01.26 -- Advancing RNA Newsletter Best Of July

JULY'S BEST FEATURED EDITORIAL

Stitching The Future: Where Enzymatic Ligation Of siRNA Stands Today

Is enzymatic ligation a futuristic dream or a current commercial reality? In this segment, industry experts Claire MacCleod and Jill Caswell explore how the sector has moved past the proof-of-concept stage into early commercialization and what this looks like/means for early adopters today. 

Targeting The Uncharted Heart: Why Next Era siRNA Belongs In Cardiology

During our conversation, Gallagher walked me through what’s keeping her up at night as she leads the company and its first siRNA candidate toward an IND, elaborating on the role RNA can play in cardiomyopathies and identifying unique challenges of developing RNA medicines.

RNA Platforms: What Transfers And What Breaks

A practical framework for distinguishing reusable RNA platform knowledge from biology-specific unknowns as therapeutics expand into new tissues and indications.

JULY'S BEST INDUSTRY INSIGHTS

Production And Scale-Up Of Key Lipids Used In mRNA Delivery Systems

Discover key strategies for overcoming challenges in the industrial-scale production of ionizable and PEG lipids to optimize mRNA vaccine formulation and address critical manufacturing requirements.

Optimizing mRNA For Success: A Guide To Stability, Delivery, And Efficacy

RNA offers exciting potential for vaccines, gene therapies, and personalized medicine, but challenges related to stability, delivery, and manufacturing persist.

mRNA Immunogenicity: Early Assessment Of Human Immune Response

Review strategies to assess the potential for human immune response following the administration of an mRNA therapeutic, the associated LNP, and the protein encoded for by the mRNA.

JULY'S BEST SOLUTIONS

Your Partner For Comprehensive Genomic Medicine Workflows

Oligonucleotide Synthesizer Overview

The Most Comprehensive Supply Chain Solutions For The Industry