Newsletter | July 1, 2026

07.01.26 -- A Mid-Year Look At The 2026 Life Sciences Industry

SPONSOR

Join Advancing RNA Live Chief Editor Anna Rose Welch and expert panelists on July 9 at 11 AM ET. for the live virtual event: The mRNA Therapeutics Regulatory Paradigm: A Closer Look. This discussion is free thanks to event sponsor Roche CustomBiotech. Can't join live? No problem. Register today and reserve your link for the On Demand connection.

FEATURED EDITORIAL

The Editors' Roundtable: A Midyear Look At The 2026 Life Sciences Industry

In this special edition of “Better Biopharma,” host Tyler Menichiello is joined by chief editors from across the Life Science Connect ecosystem to discuss what’s shaping the pharmaceutical industry in 2026. The editors reflect on recent developments in their respective spaces and make predictions on what the rest of the year has in store.

Why RNAi-Based Oncology Must Move Beyond Single-Target Thinking

RNAi therapeutics may help oncology move beyond single-target drugs by disrupting adaptive tumor survival networks driving resistance in solid tumors.

The Road To Metric-Ton siRNA Production: Is Enzymatic Ligation Ready For Commercial Volume?

Can we actually achieve metric-ton siRNA production using enzymatic ligation? While the ligation step is highly scalable, upstream "blockmer" synthesis remains the primary bottleneck. Advancing RNA Live panelists Claire MacCleod and Jill Caswell discuss the shift from "scaling out" to "scaling up" and lessons learned in the process of achieving larger-scale production. 

Following The Data To The Heart: Atrium's Quest For Next-Gen Targeted RNA Delivery

In this two-part series, Gallagher shares more about her goals for Atrium following its spin-out from Novartis, articulating what it looks like and means to “pave a path” to greater patient access in rare cardiomyopathies. Here in part one, we start with a look into the formation of Atrium, sharing the “why” behind the company’s formation and what’s next for the company’s targeted delivery platform. 

INDUSTRY INSIGHTS

The CRO Selection Checklist Sponsors Should Use Before Signing MSAs

Choosing a CRO requires more than proposals. Assess reliability, automation, GLP rigor, scientific engagement, pricing clarity, and capacity to determine who delivers defensible data on real timelines.

Engineered RNA Polymerases For High Quality, Low-Cost mRNA Manufacture

Hear how engineered enzymes improve mRNA synthesis by reducing double-stranded RNA and lowering input costs. Ensure high purity and integrity for complex, long-format therapeutic templates.

Optimizing mRNA For Success: A Guide To Stability, Delivery, And Efficacy

RNA offers exciting potential for vaccines, gene therapies, and personalized medicine, but challenges related to stability, delivery, and manufacturing persist.

Production And Scale-Up Of Key Lipids Used In mRNA Delivery Systems

Discover key strategies for overcoming challenges in the industrial-scale production of ionizable and PEG lipids to optimize mRNA vaccine formulation and address critical manufacturing requirements.

Scaling Manufacturing Flexibility For Fill-Finish Commercial Success

Pharma and biotech developers rely on adaptable fill‑finish capacity to meet evolving market demands, scale products from clinical to commercial, and respond rapidly to public‑health emergencies.

SPONSOR

Join 90+ global experts at the 5th Oligonucleotide Analytical Development & CMC Summit (Aug 17–19, Boston) to tackle the industry’s most pressing challenges in analytical characterization, impurity control, and scalable manufacturing. Gain practical insights from leading biopharma, biotech, and regulatory voices advancing oligo therapeutics across ASO, siRNA, and conjugate modalities. Explore the agenda and secure your place soon.

SOLUTIONS

Your Partner For Comprehensive Genomic Medicine Workflows