RNA Manufacturing Videos

1. Tissue Specificity and Potency & Durability 9/11/2023

   During this first segment of Cell & Gene Live, Major Trends in Next-Gen RNA Engineering, hosted by Cell & Gene’s Chief Editor, Erin Harris, Nathaniel Wang, CEO and Co-Founder, Replicate Bioscience and Sam Deutch, EVP of Research and Early Development at Nutcracker Therapeutics discuss the two major trends developing in the next generation RNA space. They cover how to more accurately target tissues to reduce off-target effects or to cross a therapeutic threshold for protein expression. In addition, they discussed how to improve the amount, quality, and longevity of expressed protein to expand the use cases for RNA.

2. The Role Of Peptones In Boosting Quality And Yield 11/4/2024

   Peptones can significantly boost CHO cell bioprocessing. We analyze their impact on diverse CHO cell lines using real-world data to assess their effects on titer, protein quality, and cell growth.

3. "Continuous Improvement:" Defining Your Purification Process & Product Specifications 4/24/2023

   In this Bioprocess Online Live panel discussion, we talk about where the greatest sources of variability are in our downstream processes and how companies should be approaching the question of “how pure is pure enough?"

4. Master mRNA Manufacturing, Purification, And Plasmid DNA Processes 3/12/2025

   Whether you're a pro or a beginner, revolutionize your process and achieve excellence today by enhancing your mRNA manufacturing skills with valuable insights and tools.

5. Establishing Analytical Methods For Emerging mRNA-Based Therapies 6/5/2023

   Here, we describe the use of cutting-edge technologies to assess critical quality attributes of both mRNA drug substances and drug products.

6. Integrating CPV And APQR Data And Workflows To Reduce Redundant Activities 11/15/2024

   Experts in the pharmaceutical industry share insights on how to effectively implement a strong, integrated CPV and APQR framework. Watch now and learn how automation enhances efficiency.

7. Sustainable Approaches To Oligonucleotide Manufacturing

   An industry expert shares about sustainable Oligo manufacturing approaches that can save time, cost, and resources – while improving purity, quality, and scalability of these promising therapeutics.

8. How Are The Costs Of mRNA-LNP Manufacturing Evolving? 2/10/2025

   Achieving cost-effective manufacturing while maintaining high quality standards today is one of the biggest challenges facing companies outsourcing mRNA/RNA development. In turn, panelists Qian Ruan, Andy Geall, and Alex Aust reflect on how and where they’ve seen the costs of mRNA-LNP manufacturing evolving/fluctuating in recent years.

9. Overcoming Regulatory, Safety/Efficacy, And Toxicity Hurdles 11/28/2022

   In this video, Russell Johnson, VP Formulation Research for RVAC Medicines, and Aalok Shah, Director of Formulation & Drug Delivery, Strand Therapeutics, discuss what industry challenges should be top of mind for experts as it relates to the regulatory paradigm, toxicity/safety, and in vivo modeling.

10. LNPs In 90 Seconds Or Less With This Benchtop IJM System 4/18/2024

    LNPs made using Helix Biotech's Nova BT IJM manufacturing system.