RNA Manufacturing Articles

  1. Beyond The m⁷G Cap: How Non-Canonical RNA Capping Could Expand RNA Therapeutics 7/16/2026

    Newly discovered non-canonical RNA caps are reshaping RNA biology and could inspire the next generation of more precise, programmable RNA therapeutics.

  2. Bridging The Atlantic: A European Executive's Guide To Entering The U.S. RNA Market (Pt. 1) 7/13/2026

    A practical roadmap for European biotech leaders navigating FDA expectations, market entry, and the strategic decisions that shape U.S. expansion.

  3. Patenting RNA Therapeutics In The Age Of AI: What Companies Must Get Right Early 7/8/2026

    As AI transforms RNA discovery, companies must rethink inventorship, obviousness, and patent strategy to secure durable intellectual property protection.

  4. Understanding Therapeutic Oligonucleotide Purification By Anion Exchange Chromatography: From Resin Architecture To Process Productivity 7/7/2026

    Explore how anion exchange chromatography improves oligonucleotide purification through smarter resin design, better separation, and scalable manufacturing.

  5. The Future Of RNA Manufacturing: Continuous Processing, AI, And Distributed Production (Pt. 3) 7/2/2026

    Continuous manufacturing, AI, modular facilities, and next-generation RNA platforms are reshaping how therapies are produced, scaled, and delivered worldwide.

  6. Can Oligonucleotide Regulations Keep Up With Manufacturing Innovation? 7/1/2026

    Here in part 2 of my TIDES takeaways, I’ll unpack which guidances we have at our disposal today in the oligo world, and what we can expect in the future. 

  7. Unlocking The Future Of mRNA 6/29/2026

    Many regulatory frameworks and analytical approaches were not originally designed for platforms like mRNA. Addressing these gaps will be essential to fully realize the potential of mRNA technologies.

  8. The Hidden Bottleneck In Advanced Therapies Isn't Science… It's Translational Friction 6/26/2026

    Scientific breakthroughs may spark innovation, but operational excellence ultimately determines which advanced therapies reach patients.

  9. RNA Therapeutics: Why CMC Strategy Will Define The Next Decade 6/25/2026

    As RNA matures into an industrial platform, long-term success will depend less on discovery and more on scalable CMC systems, integration, and execution.

  10. Rethinking The Oligonucleotide Backbone: Why RNA Therapeutics May Need A New Molecular Design Framework 6/24/2026

    New backbone chemistries could unlock greater control over delivery, specificity, and safety, expanding the molecular design space for RNA medicines.