Featured Articles

  1. A Novel RNA Lipid Nanoparticle Platform: Gene-Edited CAR T Cells For Off-The-Shelf Cancer Therapy 4/14/2022

    We report on the use of a novel lipid nanoparticle (LNP) reagent in a validated protocol to achieve successful complex gene editing in primary T cells with high efficiency while maintaining high cell viability.

  2. Accelerated Development Of Self-Amplifying mRNA (saRNA) Vaccines Using Microfluidics 4/14/2022

    We showcased the utility of microfluidics to enable low shear, rapid screening of preclinical candidates and the swift advancement to GMP-enabling studies.

  3. Oligonucleotide Development And Manufacturing Workflow 3/28/2022

    Learn more about oligo workflows and solutions for oligonucleotide process development, from scalable oligo synthesis to cleavage and deprotection, purification, and buffer exchange.

  4. How Tools And Technologies Bring Advanced Therapies To Market 3/2/2022

    Gain insight into industry trends and the tools to support the development of RNA vaccines and therapeutics.

  5. Changing The Status Quo Of Vaccine Production 3/2/2022

    Learn how the mRNA technology behind COVID-19 vaccines is poised to disrupt the status quo to improve global vaccine manufacturing capabilities.

  6. Translation Of RNA Medicines From Design To Clinic 3/2/2022

    Understand the advantages and challenges of lipid-based delivery systems for successful translation of RNA into clinical development.

  7. Accelerating The Development And Scale-Up Of mRNA Vaccines 3/2/2022

    Learn how downstream considerations can make the difference between success and failure on the path towards the commercialization of mRNA vaccines.

  8. Genomic Medicine And The Tools To Realize Its Potential 1/12/2022

    New technologies and collaborations driving the democratization of RNA therapeutics are creating an explosion of opportunity for companies pursuing the development of these transformative medicines.

  9. Key Insights Into Overcoming mRNA Process Challenges 9/8/2021

    Realizing the potential of mRNA requires focus on key areas and strategies that could help alleviate the bottlenecks in this growing market segment.

  10. mRNA Manufacturing Workflow 6/2/2021

    Therapies based on messenger RNA, such as mRNA vaccines, have revolutionary potential. Learn more about key objectives, considerations, and strategies in mRNA manufacturing.