ÄKTA Oligosynt™ Synthesizer: With A Little Help From Its Friends

The ÄKTA oligosynt™ oligonucleotide synthesizer is a compact, fully automated system designed for research and process development laboratories, offering high-yield, high-quality oligonucleotide synthesis with seamless scalability to larger systems. Its small footprint and optimized flow path enhance efficiency by minimizing reagent use and maximizing synthesis precision.

• Broad Synthesis Scale: Accommodates various synthesis scales with an optimized hold-up volume, reducing the dilution of expensive amidites and minimizing reagent waste.
• User-Friendly Interface: Flexible method editing and an interactive user interface simplify operation and streamline scale-up processes.
• Advanced Process Control: Integrated sensors measure pressure, air, temperature, UV, and conductivity, ensuring precise monitoring. The system also supports external module inputs for enhanced functionality.
• Efficient System Design: An open-front structure allows easy module access and full ventilation, while an optimized low hold-up volume enhances process efficiency.

The ÄKTA oligosynt™ includes two high-precision pumps, a pressure monitor, multiple solvent and amidite valves, a recirculation valve, a column valve, a waste valve, an I/O-box, a UV monitor, and a conductivity monitor—all essential for precision synthesis.

Controlled by UNICORN™ software, the system offers real-time monitoring, method creation, and result evaluation. Users can quickly develop synthesis methods with pre-defined templates and a sequence editor, while the transparent method overview ensures clarity with minimal reliance on macros.

The ÄKTA oligosynt™ is a powerful, scalable solution for efficient and high-quality oligonucleotide synthesis, making it an ideal choice for research and process development applications.