Newsletter | January 21, 2026

01.21.26 -- Biology, Specificity, And The Rules Of RNA Business Strategy In 2026

FEATURED EDITORIAL

Biology, Specificity, And The Rules Of RNA Business Strategy In 2026

Here, in part 3 of this outlook series, we continue our forward-looking conversation with Signify Bio CBO, Renee Williams, who shares why she hopes 2026 is the year we “focus in” on three important factors — namely our biology, our platforms, and our IP — and what this looks like/means strategically.  

To Fight Cancer, Gene Editing Needs To Solve Its Delivery Problem

The choice of delivery dictates the complexity of manufacturing, which in turn determines the eventual cost and accessibility of the therapy.

Beyond Solid Phase: Weighing Supply Chain Readiness For Liquid Phase & Hybrid Oligo Synthesis

The oligo manufacturing paradigm is facing several different evolutions whether it be the transition to liquid-phase or hybrid synthesis. In this Advancing RNA Live clip, Camp4’s Satya Kuchimanchi explores how these manufacturing advancements are impacting our supply chain needs.

INDUSTRY INSIGHTS

Practical Applications For Controlled And Safe Nucleic Acid Delivery

Look behind LNP formulation development, from ionizable lipids to scalable manufacturing through case studies, screening strategies, and flexible approaches for advancing next-generation therapeutics.

Engineered RNA Polymerases For High Quality mRNA Manufacturing

Hear how engineered enzymes improve mRNA synthesis by reducing double-stranded RNA and lowering input costs. These advancements ensure high purity and integrity for complex therapeutic templates.

Accelerating IND-Enabling Studies With Automated Bioanalysis Workflows

Reimagined as automation-first, bioanalysis shifts from being an Investigational New Drug (IND) bottleneck to a catalyst for innovation, helping companies move forward with greater confidence.

The Urgency Of Pandemic Preparedness For Sterile Injectable Manufacturing

A successful large-scale public health emergency response requires adaptable manufacturing capabilities, an experienced workforce, and effective private-public partnerships.

Robust And Cost-Effective mRNA Capping

Master the essential strategies for cost-effective and robust mRNA capping at industrial scale. Learn how to evaluate new materials and optimize your synthesis process for maximum efficiency and yield.

Beyond The Checkpoint — Next-Gen Strategies In Immuno-Oncology

Gain a clearer view of the scientific, operational, and regulatory forces propelling the next wave of oncology innovation, and what they mean for sponsors advancing cutting-edge cancer therapies.

Establishing Analytical Methods For mRNA-Based Therapies

Here, we provide a detailed description of assays for sequence identification and LNP composition in mRNA-LNP products that support the development of safe and effective mRNA therapies.

SOLUTIONS

NanoImprove The Performance Of Your Biologic Formulation

Biologics Development

Pre-Sterilized Disposable Unit Suitable For Use In cGMP Environments

Oligonucleotide Synthesizer