Newsletter | November 7, 2026

11.07.26 -- Advancing RNA Newsletter Best Of October

OCTOBER'S BEST FEATURED EDITORIAL

A New Purification Strategy For The Removal Of dsRNA Impurities From IVT mRNA Products

NIST research introduces a gentle SEC method that separates dsRNA impurities from IVT mRNA by tweaking buffer pH, achieving 81.8% target recovery without transcript damage.

Next-Gen Analytical Methods To Watch In mRNA-LNP Development

In the opening clip from this Advancing RNA Live event, AbbVie’s Elaine Peters, Sanofi’s Philippe Talaga, and Tessera’s Ilya Shestopalov share the novel methods they’ve been watching the most closely in the mRNA-LNP development space, as well as the role these methods will play in elucidating more about our drug products’ quality attributes. 

Is mRNA Manufacturing Overbuilt?

mRNA pipelines continue to advance, but has provider growth outpaced the pipeline? Let's take a closer look.

OCTOBER'S BEST INDUSTRY INSIGHTS

Defining Standards For Quality Systems In GMP IVT mRNA Production

Stay ahead in mRNA therapeutic development by mastering the essential quality systems, process controls, and analytical methods required for robust GMP production and efficient manufacturing.

Towards A Universal LNP Platform For Multiplex Engineering

Multiplex engineering of T cells for solid tumors requires precise delivery. Emerging LNP approaches enable co-delivery of RNA and DNA, offering a safer, more scalable path beyond viral vectors.

xRNA Production: The Economic Case For Continuous Manufacturing

See how a continuous manufacturing platform streamlines production to days, uses real-time quality control, and dramatically cuts costs to accelerate access to new therapies.

OCTOBER'S BEST SOLUTIONS

Quality Attribute Characterization To De-Risk mRNA Regulatory Approvals

Systems For Lipid Nanoparticle (LNP) Production

mRNA Therapeutics: Development And cGMP Manufacturing