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| Registration for INTERPHEX 2025 is officially live! Happening April 1-3 in NYC, INTERPHEX is the largest pharmaceutical and biotechnology event of the year. Join over 9,000 industry professionals and 500+ exhibitors from all over the world as we take you through the entire pharmaceutical product development lifecycle. Follow the link to claim your FREE Exhibit Hall badge. |
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By AR Welch, Editorial & Community Director, Advancing RNA | Though it’s not a question we can answer fully yet, in the first of this two-part article, CureVac CEO Alexander Zehnder starts us down the path of answering a critical question about our RNA therapies: In what ways can and should our mRNA products add value to our patients’ lives? | |
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A conversation with Derek Jantz, CSO, Tune Therapeutics | Chief Scientific Officer Derek Jantz talks about recent key innovations in gene therapy and RNA technology while considering what milestones we might see in 2025. | |
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By Peter H. Calcott, Calcott Consulting LLC | FDA's CDER recently issued a draft guidance: Nonclinical Safety Assessment of Oligonucleotide-Based Therapeutics. This article provides a summary and analysis. | |
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In this Advancing RNA Live clip, BioNTech’s Ben Muir and Hopewell Therapeutics’ Kate Zhang share their perspectives on the most exciting novel screening methods, innovative preclinical models, and next-gen technologies they hope can/will eventually help us bridge the translation gap between preclinical models and the clinic. |
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| mRNA Product Purification Process Strategies | Article | Cytiva | Impurities from IVT can induce undesired immune responses and negatively impact translation efficiency. Explore the pros and cons of each option for mRNA purification. |
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| Study Viral Infection In Resting Human CD4+ T Cells | Application Note | Synthego Corporation | Explore a study proving how synthetic single guide RNAs were used to optimize the editing conditions for resting human CD4+ T cells and maintain high cell viability for several weeks post Nucleofection. |
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| Essential Strategies For IVT Optimization | Article | Roche CustomBiotech | Optimizing in vitro transcription (IVT) for mRNA is crucial to improving the stability of these molecules and enabling their large-scale production. |
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