Newsletter | January 22, 2025

01.22.25 -- Top 5 mRNA/RNA Advancements Of 2024

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2025 BioPlan's 22nd Annual Survey--Biopharmaceutical Manufacturing

For over 20 years, we continue to be the leader in providing the biopharma industry's most comprehensive benchmarking analysis. We invite you to participate in our 22nd Annual Survey in Biopharmaceutical Manufacturing! For all completed, qualified responses, we'll send an Amazon egift card, a copy of the summary results (mid-2025), and our 2025 Top Trends in Biomanufacturing White Paper.

FEATURED EDITORIAL

Top 5 mRNA/RNA Advancements Of 2024 (Part 2)

As I took stock of the year behind us, there were five overarching ways in which I saw our industry taking steps forward and finding itself on sturdier scientific and clinical footing. Here, in the second of this two-part article, I continue down this list with my last three takeaways.

RNA In 2025: Looking Beyond The Horizon Of First-Generation Success

As we enter 2025, RNA therapeutics are poised to command significant attention from industry leaders as well as emerging players.

R&D & CMC Priorities For LNPs Beyond Cell-Specific Delivery

It goes without saying that achieving cell-specific delivery is the most often discussed challenge facing the RNA-LNP field near- and long-term. However, as these three LNP experts share in this Advancing RNA Live clip, they have a whole list of additional R&D and CMC priorities we must address/accomplish to improve RNA-LNPs’ efficacy in personalized and gene therapy approaches.

Is Your CDMO Using These AI Solutions In CMC For Oligos & Peptides?

Oligonucleotides and peptides require precise, scalable, and compliant production. CDMOs are integrating AI-driven technologies to answer the call. Many of these technologies are notable for specific needs.

INDUSTRY INSIGHTS

Structural Characterization Of RNA And Detection Of RNA-Ligand Binding

Delve into the intricacies of riboswitch behavior and ligand interactions and gain valuable insights into gene regulation and potential therapeutic targets.

Optimized And Scalable LNP Composition For RNA Vaccine Delivery

Explore results from a study screening novel LNP formulations for physicochemical attributes, in vitro potency, and in vivo immunogenicity in both SARS-CoV-2 and influenza vaccine applications.

Manufacturing Strategies For mRNA Vaccines And Therapeutics

mRNA has emerged as a promising modality offering a great deal of versatility for a wide range of therapeutics and vaccines with its use of non-viral delivery systems.

Accelerating Your mRNA Drug Development With Analytics

To stay ahead in the competitive landscape of mRNA development, adopt a comprehensive QC strategy today and begin conducting meaningful tests to ensure the quality of your test articles.

Future Proof Your Process Scale Workflow

Our goal is the same as yours: to fight disease, one new biologic at a time. Discover how to future-proof your process scale workflow, from starting bases to tangential flow filtration.

Nanoscale Technology's Potential: A Fireside Chat With Industry Leaders

Nanoform CEO Edward Haeggstrom and Shawn Davies, head of drug delivery, biopharmaceuticals development, AstraZeneca, discuss the potential of nanoscale medicines and delivery devices.

Optimizing Biologics Manufacturing Processes With Raw Materials

Improve your commercial manufacturing process with advice from regulatory and raw materials experts on the development journey from pre-clinical to licensure.