Quality Control In IVT RNA Workflow Using Agilent TapeStation Systems

Quality control is a critical step in the in vitro transcription (IVT) RNA workflow, especially when RNA is destined for therapeutic applications like vaccines, gene therapies, and cancer treatments. Discover how automated electrophoresis systems—specifically the TapeStation—can be used to assess the size and purity of both DNA templates and final IVT RNA products. Accurate sizing ensures proper template construction and minimizes off-target amplification, while purity checks help confirm RNA integrity for downstream use. The TapeStation system enables fast switching between DNA and RNA analysis, offering reliable measurements across varying sample concentrations. Data from multiple samples demonstrate low error rates and high precision, reinforcing the system’s value in optimizing IVT workflows. For researchers working with IVT RNA, gain practical insights into improving QC efficiency and confidence in final product quality.

Explore the full application note to see how TapeStation can streamline your RNA production process.