Newsletter | September 25, 2024

09.25.24 -- Pivoting To RNA With Circio's Dr. Erik Digman Wiklund

SPONSOR

Reserve your space for our Virtual Symposium on October 08! Moderated by Dr. Eleni Samaridou, Principal Scientist, Early Formulation Screening Service at MilliporeSigma, the symposium will feature Dr. Roland Böttger, Senior Scientist at CureVac, and other industry experts. Presentations will outline utilizing isolator filling technology for LNP manufacturing, navigating regulations for quality control testing of mRNA/LNP products and tailoring the immunogenicity profile in an mRNA-LNP vaccine platform to extend the shelf-life stability. Register now!

FEATURED EDITORIAL

Pivoting To RNA With Circio's Dr. Erik Digman Wiklund

This week, it’s another “Business of Biotech-meets-Business-of-RNA” takeover with Circio CEO Erik Digman Wiklund, Ph.D. and guest co-host Anna Rose Welch of Advancing RNA. While Circio’s legacy is in cancer immunology (it still boasts a cancer vaccine candidate targeting KRAS driver mutations), the company made a bold pivot, of sorts, when it committed headlong to the circular RNA future. Now, it’s in the throes of fine-tuning a platform for the development of novel circRNA medicines for rare disease, vaccines, and cancer.

INDUSTRY INSIGHTS

Translation Of RNA Medicines From Design To Clinic

Understand the advantages and challenges of lipid-based delivery systems for successful translation of RNA into clinical development.

Talent And Supply: Building A Foundation For The Future Of Biopharma

Read how to create future-ready facilities supported by advanced scientific knowledge and a secure supply chain that can handle the unprecedented demands and constraints of a post-COVID world.

How mRNA Technology Engineers Next-Generation Antibodies

Monoclonal antibodies (mAbs) stand as pivotal drug products and biochemical reagents in the 21st century. Explore how mRNA-encoded antigens could revolutionize antibody discovery.

Determining RNA Integrity And Purity By Capillary Gel Electrophoresis

To ensure mRNA product quality, it's important to confirm the integrity of the RNA. Examine the results of a study challenging the performance of the CGE method in assessing mRNA integrity and purity.

A New Centre For Continuous mRNA Manufacturing

Explore how a partnership between academia, regulatory agencies, and manufacturing organizations has the potential to reshape the way we produce and distribute mRNA-based therapies.

SPONSOR

Explore the forefront of precision medicine at the Advancing Precision Medicine Conference and Exhibition in Philadelphia, November 1-2. Engage with cutting-edge research featuring experts who are shaping the future of healthcare. Discover new insights into personalized treatments, genomic advancements, and innovative technologies revolutionizing patient care. Expand your knowledge and network with leaders driving the field forward. View the agenda and register today!

ADDITIONAL FEATURED EDITORIAL

A Perfect Pair? Combining Keytruda And mRNA To Optimize Cancer Outcomes

AdventHealth's Guru Sonpavde, MD credits the patient-centric trial design, the city’s diversity, and the staff's expert execution for giving bladder cancer patients a chance at a quicker and fuller recovery. 

The State Of CircRNA Analytical Development

Advancing RNA LIVE panelist Jim Nolan of Sail Biomedicines fills us in on the extent to which we can rely on the linear mRNA analytical foundations established today.