Datasheet | November 25, 2025

Phosphitylating And Phosphorylating Agents

Source: Entegris, Inc.
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Phosphitylating and phosphorylating agents are critical materials for producing amidites used in DNA and RNA nucleotide oligomers, also known as oligonucleotides. These agents enable the reproducible and economical manufacturing of high-quality, high-purity products, ensuring consistent yields for applications like synthesizing DNA- and RNA-based drugs, and preparing oligonucleotide sequences for bioprocessing, cell and gene therapy, and diagnostics.

This datasheet details a portfolio of agents tailored for specific manufacturing needs, which can be provided from grams to metric ton quantities through scale-up and full commercialization. This includes a product portfolio with various compounds, their CAS numbers, and structures, Phos-reagent and Bis(diisopropyamino) chlorophosphine. Explore the full list of products and specifications to find the ideal agents for your custom synthesis solutions.

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