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By AR Welch, Editorial & Community Director, Advancing RNA | Here, I outline three overarching words of wisdom I gleaned from Life Edit Therapeutics’ April Sena; Tune Therapeutics’ Tyler Goodwin; and University of Sheffield’s Adi on how the mRNA/RNA industry can better control production costs — particularly as it relates to raw material sourcing and usage. | |
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By Nero Haralalka, TBM Consulting Group | The U.S. tariffs on trading partners bring a whole new set of challenges, but there are tactics and strategies companies can deploy to help offset the cost and operational impacts. | |
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There remain a lot of gaps in our understanding of plasmid quality, particularly for high-quality mRNA production (as opposed to viral vector production). In this segment of a recent Advancing RNA Live panel, speakers Adi Nair, Tyler Goodwin, and April Sena highlight their biggest questions around plasmid DNA quality, as well as the pros and cons of some of the analytical methods upon which we’re relying most heavily today to assess plasmid quality. |
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In this episode of the Cell & Gene podcast, Host Erin Harris speaks with Alicia Zhou, Ph.D., CEO of the Cancer Research Institute (CRI), about CRI’s mission to advance cancer immunotherapy and the critical role of federal funding, particularly from the NIH, in supporting basic and translational cancer research. |
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| Fast And Efficient Extraction Of mRNA From IVT Mixtures | Poster | By N. Mencin, U. Černigoj, S. Peljhan, Š. Peršič, P. Gagnon, and A. Štrancar, Sartorius | Here, a fast and efficient way to purify polyadenylated mRNA using affinity chromatography on the CIMmultus Oligo dT column is presented. |
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| Regulatory Frameworks For mRNA Therapeutics | White Paper | MilliporeSigma | The RNA therapeutics and vaccines market has grown rapidly, driven by siRNA and mRNA technologies. Learn how these advancements are being applied to cancer vaccines and innovative therapeutics. |
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| Empowering A New Era Of Patient-Centric Medicines | Podcast | Nanoform | Discover the challenges pharma companies are facing as they switch focus as well as the actions and technologies companies are implementing to help achieve a brighter future for patients. |
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| Regulatory Compliance In Clinical Research | Article | Novotech | Understand the critical aspects of regulatory compliance, and gain insights into how you can safeguard participant rights and ensuring the integrity of clinical research. |
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| Join Advancing RNA Live for a dynamic discussion on the latest regulatory guidances from global agencies and what they mean for mRNA vaccine and therapeutic development. Discover key challenges, actionable insights, and best practices to accelerate your programs—no matter your approach. Don’t miss this opportunity to gain expert-driven clarity. Registration is free thanks to the support of Roche CustomBiotech. |
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