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| Designing a Plasmid DNA Downstream Purification Process | Discover in our technical article the Downstream Purification in the Plasmid DNA (pDNA) Manufacturing Process. Plasmid DNA (pDNA) is an essential component of, and key technology for production of viral vector, mRNA, and vaccine therapies. The far-reaching potential of novel therapeutic modalities and vaccines that rely on pDNA is driving increased demand and the need for improved production strategies – Read Now! |
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By AR Welch, Editorial & Community Director, Advancing RNA | In the first- of this two-part article, Koeris and I ford through some of the most prominent delivery-vehicle development pain-points that don’t get nearly as much conversation as they should today. |
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When asked which specific topic they’d like to see discussed more regularly in the future as it relates to our supply chains, Featured speakers for the "Got Raw Materials? The State Of The mRNA Supply Chain" event were aligned around this one absolutely critical topic... |
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By Takehiro Okumura and Zeb Khan, Takeda Pharmaceuticals | Would you ever need to follow GMP standards in workspaces where GMP is not required or possible? This article digs into why, when, and how to follow the principles of GMP. |
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Hosted by Advancing RNA's own Anna Rose Welch, ARW on RNA puts a creative spin on the emerging mRNA + RNA therapeutics industry. Here, in Episode 4, Welch explores the parallels that exist between the oft-overlooked history of Michelangelo's David and the mRNA therapeutics sector's own R&D history, as well as where the mRNA space hopes to move in the future. |
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| Advancing An LNP Formulation To Clinical And Commercial Manufacturing | White Paper | By M. Karwa, Ph.D., T. Demuth, Ph.D., and G. Béalle, Ph.D., MilliporeSigma | Lipid selection impacts the final LNP drug product and the LNP process. Review critical quality considerations for lipids and the process requirements for successful commercial-scale manufacturing. |
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| The Future of Biotechnology in Individualized Medicine conference will explore the ongoing evolution of genomics from a tool for diagnostic breakthroughs to a driver of revolutionary therapeutics. Organized jointly by the Scripps Research Translational Institute, Actio Biosciences, and Advancing Precision Medicine, attendees will hear from renowned leaders from across academia and industry speak on the most recent innovation and trends in genomic medicine. View the full agenda and register here. |
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