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Process development and formulation services for pDNA and mRNA
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Cytiva now offers process development and formulation services for plasmid DNA (pDNA), messenger RNA (mRNA) and lipid nanoparticles (LNPs), delivering end-to-end support for early-stage biotechs and biopharmas seeking to accelerate development, de-risk scale-up, and prepare for clinical milestones. Customers retain full ownership of their process knowledge and can move from process development to cGMP manufacturing with confidence and speed.
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By Arnaud Deladeriere, Ph.D., Cell&Gene Consulting Inc.
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Decisions in cell and gene therapy are not about aligning with arbitrary clinical phases but about balancing risk.
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In this Advancing RNA clip, Jim Martineau, of Nosis Bio, and Sean Kevlahan from Nanite Bio, walk us through some of the benefits of working with receptor-based targeting and advanced polymer systems — each of which are emerging as promising alternatives to lipid nanoparticles.
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By AR Welch, Editorial & Community Director, Advancing RNA
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As many of the presentations throughout the two-day USP quality forum revealed, we’re doing what we must to understand the benefits and the limitations of our methods. Yes, this is painstaking and expensive work. But understanding our methods is also one of the critical steps toward a future in which we can rely upon platform analytical procedures and — channeling our inner Britney Spears — say “[Ooo], I did it again!” to the regulatory agencies for each of the subsequent molecules in our pipelines.
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Assigning IR Absorption Bands For RNA Building Blocks Using MMS
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Application Note | RedShiftBio
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Explore the power of Microfluidic Modulation Spectroscopy (MMS) in identifying RNA base signatures. This study analyzes vibrational modes of A, G, C, and U, revealing insights into electronic environments and molecular interactions.
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Elevating mRNA Manufacturing Toward GMP-Readiness
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White Paper | MilliporeSigma
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The mRNA Technology Transfer Program empowers low- and middle-income countries (LMICs) with scalable vaccine production. Learn about a partnership that drives mRNA innovation and sets a global blueprint for equitable health access.
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Ophthalmic Drug Delivery
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Article | By Dr. Tamas Solymosi\, Nanoform
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Explore the challenges to effective delivery of drugs to the eye, intricacies of ophthalmic drug delivery, and advantages of nanoparticles as an enabling technology for ocular drug-delivery systems.
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Comparison Of HIC Monolithic Support For Sample Displacement Of pDNA
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Application Note | Sartorius
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Competing adsorption in sample displacement chromatography utilizes the chromatographic resin's binding capacity more efficiently and increases the chromatographic step's productivity. Learn about three monolithic chromatographic supports and their applicability for sample displacement of pDNA.
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Advancing the Future of Cell & Gene Therapy
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This 11-12 November, Cell 2025 unites 1,000+ experts across the CGT value chain to solve key challenges, from scalable bioprocessing and regulatory hurdles to accelerating development. Gain insights across cell culture, therapy development, and CGT manufacturing, and learn from world-renowned leaders Bobby Gaspar (Orchard Therapeutics), Christof Von Kalle, (Research Clinic Luxemburg), and Dame Molly Stevens (University of Oxford). Register Now
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